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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K5
All Species:
22.73
Human Site:
T1059
Identified Species:
50
UniProt:
Q99683
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99683
NP_005914.1
1374
154537
T1059
A
T
L
H
R
I
L
T
E
D
Q
D
K
I
V
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
T1060
A
T
L
H
R
I
L
T
E
D
Q
D
K
I
V
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
E1010
A
M
L
A
A
V
L
E
Q
E
L
P
A
L
A
Dog
Lupus familis
XP_533420
1645
181128
T1330
A
T
L
H
R
I
L
T
E
D
Q
D
K
V
V
Cat
Felis silvestris
Mouse
Mus musculus
O35099
1380
154441
T1066
A
T
L
H
R
I
L
T
E
D
Q
D
K
V
V
Rat
Rattus norvegicus
XP_001073260
1338
150427
T1023
A
T
L
H
R
I
L
T
E
D
Q
D
K
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
E965
T
L
V
T
S
L
R
E
F
V
R
S
T
D
R
Chicken
Gallus gallus
XP_419725
1260
143069
A963
M
E
A
L
A
Q
G
A
E
E
P
K
L
K
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
T1050
A
T
L
H
R
I
L
T
E
D
R
E
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477089
1363
155478
A965
T
T
L
S
K
V
L
A
L
D
E
S
K
I
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
A990
M
T
L
N
H
G
I
A
L
F
I
K
Q
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
44.9
68
N.A.
94.1
92.7
N.A.
84.4
80.4
N.A.
71.7
N.A.
40.6
N.A.
N.A.
44.6
Protein Similarity:
100
99.4
61.3
73.1
N.A.
95.8
94.4
N.A.
87.8
87
N.A.
84.1
N.A.
58.2
N.A.
N.A.
60.7
P-Site Identity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
0
6.6
N.A.
86.6
N.A.
40
N.A.
N.A.
13.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
20
13.3
N.A.
100
N.A.
60
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
10
10
19
0
0
28
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
64
0
46
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
19
64
19
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
55
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
55
10
0
0
0
10
0
0
37
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
19
64
10
0
% K
% Leu:
0
10
82
10
0
10
73
0
19
0
10
0
10
10
0
% L
% Met:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
46
0
10
0
0
% Q
% Arg:
0
0
0
0
55
0
10
0
0
0
19
0
0
10
10
% R
% Ser:
0
0
0
10
10
0
0
0
0
0
0
19
0
0
0
% S
% Thr:
19
73
0
10
0
0
0
55
0
0
0
0
10
0
0
% T
% Val:
0
0
10
0
0
19
0
0
0
10
0
0
0
28
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _